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Calquence fails to prevent respiratory failure in COVID-19 patients
europeanpharmaceuticalreview
November 16, 2020
AstraZenaca reveals Calquence (acalabrutinib) did not increase the proportion of hospitalised COVID-19 patients who remained alive and free of respiratory failure.
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Flamma Continues Veklury Partnership with Gilead for Covid-19
americanpharmaceuticalreview
November 16, 2020
Flamma entered into an agreement with Gilead earlier this year to be part of the network of manufacturers contributing to the Veklury? (remdesivir) supply chain.
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Study recommends steroid treatment should be given only to sickest COVID-19 patients
expresspharma
November 16, 2020
While dexamethasone and other steroids are prescribed to treat cytokine storms, these drugs can backfire in patients whose immune response is already suppressed.
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Swissmedic Begins Rolling Review of Moderna’s mRNA COVID-19 Vax
contractpharma
November 16, 2020
Moderna completed enrollment of its Phase 3 COVE study of mRNA-1273 on October 22.
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JAMA Reports Fluvoxamine as Potential Early Treatment for COVID-19
prnewswire
November 13, 2020
The COVID-19 Early Treatment Fund (CETF), announced that JAMA, The Journal of the American Medical Association, published the results of a Washington University School of Medicine in St. Louis double-blind, randomized controlled clinical trial that ...
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Lack of skill and talent biggest challenge to digital transformation in pharma
europeanpharmaceuticalreview
November 13, 2020
A report has found that the biggest hurdle for digital transformation in pharma is a lack of specific skills and talents, followed by organisational silos.
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FDA grants emergency use authorisation to COVID-19 antibody bamlanivimab
europeanpharmaceuticalreview
November 13, 2020
The neutralising antibody therapy bamlanivimab (LY-CoV555) is authorised for emergency use in recently diagnosed patients who are at risk of developing severe COVID-19.
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Stem cell therapy trial for COVID-19 patients with ARDS advised to continue
europeanpharmaceuticalreview
November 13, 2020
The trial’s independent Data Safety Monitoring Board (DSMB) recommended that the Phase III study evaluating remestemcel-L continue based on the second interim analysis.
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Zydus concludes Phase II trials of Pegylated Interferon alpha-2b for COVID-19, to begin Phase III trials
expresspharma
November 13, 2020
In 19 out of 20 patients, a single 1 mcg/kg dose of the drug demonstrated viral clearance as assessed by RT-PCR and a significant improvement in clinical symptoms, informs the company.
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Gates Foundation offers $70 mn additional funding for COVID-19 vaccines
expresspharma
November 13, 2020
$50 million will go to the COVAX Advance Market Commitment (AMC) and $20 million to the Coalition for Epidemic Preparedness Innovations (CEPI).