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Zydus Cadila files IND application for ZYIL1, NLRP3 inflammasome inhibitor
expresspharma
November 05, 2020
Zydus announced that it has filed the IND application of ZYIL1, a novel oral small molecule NLRP3 inhibitor candidate. Following up on its initiatives to fight COVID 19 with diagnostics, vaccines and therapeutics, the company is now focussing on ...
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Agenus Doses First COVID-19 Patient with iNKT Cell Therapy
americanpharmaceuticalreview
November 05, 2020
Agenus announced the dosing of the first COVID-19 patient with agenT-797, an allogeneic cell therapy, through its subsidiary, AgenTus Therapeutics. The trial is being led by Dr. Koen van Besien at ...
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Oxford BioDynamics enters strategic partnership with Boca Biolistics
pharmatimes
November 05, 2020
Oxford BioDynamics has entered a strategic partnership with US-based biorepository, reference lab and contract research organisation Boca Biolistics.
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UK regulator initiates rolling review of AstraZeneca’s vaccine for Covid-19
pharmaceutical-technology
November 04, 2020
UK’s Medicines and Healthcare Products Regulatory Agency (MHRA) has initiated the accelerated rolling review of AstraZeneca’s potential vaccine to treat Covid-19.
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Covid-19 cases increase ahead of US presidential election
pharmaceutical-technology
November 04, 2020
Ahead of the US presidential election, Midwestern states in the country are experiencing a record number of Covid-19-related hospitalisations indicating an exponential surge in cases.
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Experts seek data on remdesivir and COVID-19 treatment-related products
expresspharma
November 04, 2020
Recently, Dr Reddy’s Laboratories’ plea to change the regulatory approval status of remdesivir injection, COVID-19 treatment drug, from restricted emergency use to full marketing authorisation was rejected by COVID-19 subject expert committee (SEC) of ...
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CEPI extends partnership with Clover Biopharma to fund COVID-19 vaccine candidate
expresspharma
November 04, 2020
CEPI to fund the development of Clover’s protein-based S-Trimer vaccine candidate through to licensure, including a global pivotal Phase 2/3 efficacy clinical study beginning before the end of 2020.
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New study assessing antibiotics for COVID-19 sepsis
pharmatimes
November 04, 2020
Researchers from an NIHR-funded study are looking at how to improve the use of antibiotics for patients with COVID-19 who are at risk of developing sepsis and thus organ failure and death.
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RevImmune Advances New COVID-19 Immunotherapy
americanpharmaceuticalreview
November 04, 2020
RevImmune announced its "ILIAD-7" international randomized controlled Phase 2 trial in patients critically ill with COVID-19, is now enrolling patients at five sites in the U.S.
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Humanigen announces first patient dosed in NIH ACTIV-5/Big Effect trial evaluating lenzilumab for Covid-19
pharmaceutical-business-review
November 04, 2020
Humanigen, a clinical stage biopharmaceutical company focused on preventing and treating an immune hyper-response called ‘cytokine storm,’ announced that the first patient has been dosed at the Emory University School of Medicine in Atlanta, Georgia as...