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WHO halts hydroxychloroquine, HIV drugs in COVID trials after failure to reduce death expresspharma
July 07, 2020
The setback came as the WHO also reported more than 200,000 new cases globally of the disease for the first time in a single day.
Immune Regulation and DynPort Vaccine Company partner to advance COVID-19 drug in clinical trials expresspharma
July 07, 2020
Immune Regulation’s drug candidate IRL201104 has been shown to quickly and markedly reduce excessive infiltration of neutrophils in lungs in a preclinical model of acute lung inflammation.
Merck initiates first clinical trial of TLR7 and 8 inhibitor as a potential treatment for severe symptoms of COVID-19 infection worldpharmanews
July 06, 2020
Merck, a leading science and technology company, announced the U.S. Food and Drug Administration (FDA) has cleared its investigational new drug application (IND) for M5049 for the treatment of patients with Covid-19 pneumonia.
Russia’s RDIF, ChemRar to boost production of Avifavir for Covid-19 pharmaceutical-technology
July 06, 2020
A joint venture established by the Russian Direct Investment Fund (RDIF) and ChemRar Group is set to boost production of Avifavir, which secured temporary approval from the Russian government to treat Covid-19.
Regeneron, Sanofi arthritis drug fails COVID-19 study expresspharma
July 06, 2020
Previous trial results had shown that the drug did not help patients with less severe COVID-19, the disease caused by the novel coronavirus.
New COVID-19 strain dominates global cases of virus, it is more infectious but not more severe expresspharma
July 06, 2020
The variant, named ‘D614G’, makes a small but effective change in the ‘spike’ glycoprotein that protrudes from the surface of the virus, which it uses to enter and infect human cells.
WHO to discontinue hydroxycholorquine trial for COVID-19 expresspharma
July 06, 2020
It said interim results show hydroxychloroquine “produce little or no reduction in the mortality of hospitalised COVID-19 patients when compared to standard of care.”
EUSA Pharma bags US approval for COVID-19 trial pharmatimes
July 03, 2020
US regulators have issued a green light for a Phase III clinical trial testing EUSA Pharma's for patients seriously ill with COVID-19 associated Acute Respiratory Distress Syndrome (ARDS).
Sanofi, Regeneron's pull plug on Kevzara COVID-19 trial pharmatimes
July 03, 2020
Sanofi and Regeneron have reported that a late-stage trial assessing the potential of arthritis drug Kevzara (sarilumab) has been stopped after it failed to hit targets.
Newer variant of COVID-19-causing virus dominates global infections worldpharmanews
July 03, 2020
Research out today in the journal Cell shows that a specific change in the SARS-CoV-2 coronavirus virus genome, previously associated with increased viral transmission and the spread of COVID-19, is more infectious in cell culture.